Table 1 Result of the comparison of the two versions of the fed batch process.
From: Platform process for production of monoclonal antibodies for research purposes – improvement option
mAb | Current version: Version 6 | New version: Version 8 | ||||
|---|---|---|---|---|---|---|
ICA*) | Lactate | mAb | ICA | Lactate | mAb | |
10E6 viable cell days/ml | mmol/l | g/l | 10E6 viable cell days/ml | mmol/l | g/l | |
C | 108 | 57 | 3.5 | 92 | 28 | 7.1 |
D | 103 | 61 | 2.2 | 90 | 29 | 5.2 |
E | 162 | 65 | 5.5 | 104 | 17 | 9.0 |
H | 100 | 55 | 3.2 | 120 | 25 | 7.0 |
J | 148 | 62 | 3.2 | 164 | 21 | 4.3 |