Figure 1

Association and linkage scans for 18 breast cancer related transcripts. Black curves are LOD scores from the linkage scans with the height of each row standardized by LOD = 5 and red dotted reference lines indicating LOD = 3. Top 30 SNPs with the strongest overall (blue ticks) and interaction (red ticks) association signal for a given expression trait are marked. A green triangle points out the genome alignment locus of the given expression sequence of that row, while gray dots are alignment loci of other breast cancer related expression sequences (including those were not studied in this paper).