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Table 2 Sensitivity and specificity of three SNPs associations with two different phenotypes (50 replications)

From: Rheumatoid arthritis, item response theory, Blom transformation, and mixed models

  Sensitivity (%) Specificity (%)
Traits(s) transformation SNP1a SNP2&3b SNP1-3 GENE1c GENE2 SNP1 SNP2&3 SNP1-3 GENE1 GENE2
IRT latent variable 24.00 7.00 12.70 7.30 4.80 94.79 94.79 94.79 94.80 94.78
Anti-CCP Blom transformation 100.00 6.00 37.30 46.20 10.10 93.21 93.20 93.21 93.42 93.21
  1. aSNP1 is located at 32,484,648 bp and labeled as m3437.
  2. bSNP2&3 flank the location 37,233,784 bp and labeled as m3916 and m3917.
  3. cGENE1 and GENE2 represent, respectively, a region ~500 kb around SNP1 (assumed as locus DR) and around SNP2 and SNP3 (Locus D).