Skip to main content

Table 1 Principal components of heritability and linkage analysis

From: Clustering and principal-components approach based on heritability for mapping multiple gene expressions

  Principal components analysis Linkage analysis
First 3 components in each cluster Clustering method Cluster No. members Cumulative % variation explained Genome-wide peak t-value Genome-wide peak p-value SNP Peak location
A.1 Classical A 10 36% 3.7 1.25 × 10-4 rs1333050 chr 9 (43.9 cM)
A.2 Classical A 10 58% 3.01 1.00 × 10-3 rs983795 chr 14 (77.3 cM)
A.3 Classical A 10 72% 3.59 1.90 × 10-4 rs332364 chr 3 (93.3 cM)
B.1 Proposed B 8 37% 4.31 1.06 × 10-5 rs941838 chr 14 (113 cM)
B.2 Proposed B 8 62% 4.82 1.02 × 10-6 rs1955897 chr 14 (110.5 cM)
B.3 Proposed B 8 77% 4.06 2.93 × 10-5 rs297675 chr 20 (11.9 cM)
C.1 Proposed C 11 41% 4.46 5.31 × 10-6 rs1892302 chr 10 (27 cM)
C.2 Proposed C 11 58% 4.99 4.62 × 10-7 rs2206185 chr 6 (111.2 cM)
C.3 Proposed C 11 68% 5.36 7.35 × 10-8 rs1950475 chr 14 (109 cM)
D.1 Proposed D 10 38% 4.61 2.78 × 10-6 rs1950475 chr 14 (109.6 cM)
D.2 Proposed D 10 60% 3.32 4.95 × 10-4 rs739495 chr 19 (58.5 cM)
D.3 Proposed D 10 74% 3.34 4.62 × 10-4 rs1955897 chr 14 (110.5 cM)