BMC Proceedings

Table 3 Problem 1 empirical power under the additive trait model with varying heritability and causal SNPs

From: One-stage design is empirically more powerful than two-stage design for family-based genome-wide association studies

	Power^a
	rs893613		rs1983011
	h² = 0.25	h² = 0.5	h² = 0.25	h² = 0.5
2-stage (n = 10)	0.5	0.92	0.38	0.91
1-stage CLRT (n = 1509)	0.88	1	0.81	1

^aNominal type I error rate of α = 0.05, using a Bonferroni correction

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