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Table 3 Problem 1 empirical power under the additive trait model with varying heritability and causal SNPs

From: One-stage design is empirically more powerful than two-stage design for family-based genome-wide association studies

  Powera
  rs893613 rs1983011
  h2 = 0.25 h2 = 0.5 h2 = 0.25 h2 = 0.5
2-stage (n = 10) 0.5 0.92 0.38 0.91
1-stage CLRT (n = 1509) 0.88 1 0.81 1
  1. aNominal type I error rate of α = 0.05, using a Bonferroni correction