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Table 3 Problem 1 empirical power under the additive trait model with varying heritability and causal SNPs

From: One-stage design is empirically more powerful than two-stage design for family-based genome-wide association studies

 

Powera

 

rs893613

rs1983011

 

h2 = 0.25

h2 = 0.5

h2 = 0.25

h2 = 0.5

2-stage (n = 10)

0.5

0.92

0.38

0.91

1-stage CLRT (n = 1509)

0.88

1

0.81

1

  1. aNominal type I error rate of α = 0.05, using a Bonferroni correction
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BMC Proceedings

ISSN: 1753-6561

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