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Table 2 Evidence of interaction between multiple loci and gender in cases

From: Pattern-based mining strategy to detect multi-locus association and gene × environment interaction

Marker Names Typea p-Value
SNP0177 Female only 0.006738
SNP0177 Male only 0.105399 b
SNP0177 With gender partition 0.012727
SNP0177 Without gender partition 0.013569
SNP0615 Female only 0.002029
SNP0615 Male only 0.246597
SNP0615 With gender partition 0.009541
SNP0615 Without gender partition 0.004517
SNP0177–SNP0615 Female only 0.001092
SNP0177–SNP0615 Male only 0.001182
SNP0177–SNP0615 With gender partition 0.000024
SNP0177–SNP0615 Without gender partition 0.000862
  1. aFour variations of the 2 × N contingency table were constructed for each marker in the significant patterns in Table 1 and for each significant pattern with the observed N genotypes as rows. Each contingency table has two columns for case and control. In "Without gender partition", individuals were grouped and allocated to table cells according to genotypes regardless of their gender. In "With gender partition", individuals were grouped together according to genotypes and gender with each combination of genotype and gender as a row. In "Males only", only males were grouped and allocated to table cells according to genotypes. In "Females only", only females were grouped and allocated to table cells according to genotypes.
  2. bBold font indicates results for males only.