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Table 1 Distribution of ascertained triads

From: The impact of complex informative missingness on the validity of the transmission/disequilibrium test (TDT)

Affected offspring Father Mother Probability Obs.
B1B1 B1B1 B1B1 P22,2 = μ2 × (1-Pf11) × (1-Pm11) × (1-Po11) M22,2
  B1B1 B1B2 P22,1 = μν × (1-Pf11) × (1-Pm12) × (1-Po11) M22,1
  B1B2 B1B1 P21,2 = μν × (1-Pf12) × (1-Pm11) × (1-Po11) M21,2
  B1B2 B1B2 P21,1 = ν2 × (1-Pf12) × (1-Pm12) × (1-Po11) M21,1
B1B2 B1B1 B1B2 P12,1 = μζ × (1-Pf11) × (1-Pm12) × (1-Po12) M12,1
  B1B2 B1B1 P11,2 = μζ × (1-Pf12) × (1-Pm11) × (1-Po12) M11,2
  B1B1 B2B2 P12,0 = μτ × (1-Pf11) × (1-Pm22) × (1-Po12) M12,0
  B2B2 B1B1 P10,2 = μτ × (1-Pf22) × (1-Pm11) × (1-Po12) M10,2
  B1B2 B1B2 P11,1 = 2νζ × (1-Pf12) × (1-Pm12) × (1-Po12) M11,1
  B1B2 B2B2 P11,0 = ντ × (1-Pf12) × (1-Pm22) × (1-Po12) M11,0
  B2B2 B1B2 P10,1 = ντ × (1-Pf22) × (1-Pm12)× (1-Po12) M10,1
B2B2 B1B2 B1B2 P01,1 = ζ2 × (1-Pf12) × (1-Pm12) × (1-Po22) M01,1
  B1B2 B2B2 P01,0 = ζτ × (1-Pf12) × (1-Pm22) × (1-Po22) M01,0
  B2B2 B1B2 P00,1 = ζτ × (1-Pf22) × (1-Pm12) × (1-Po22) M00,1
  B2B2 B2B2 P00,0 = τ2 × (1-Pf22) × (1-Pm22) × (1-Po22) M00,0
Total    S u m = i , j , k P i j , k MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaieaacqWFtbWucqWF1bqDcqWFTbqBcqGH9aqpdaaeqbqaaiabdcfaqnaaDaaaleaacqWGPbqAaeaacqWGQbGAcqGGSaalcqWGRbWAaaaabaGaemyAaKMaeiilaWIaemOAaOMaeiilaWIaem4AaSgabeqdcqGHris5aaaa@3FF0@ Ntriads