Skip to main content

Table 1 Power of haplotype- and cluster-based association analyses at the HLA-DRB1 locusa

From: Density-based clustering in haplotype analysis for association mapping

 

Powerb

 
 

α = 0.05

α = 0.01

Mean d.f.c

6 Markers d

   

   Haplotypes

0.672

0.379

9.36

   Clusters

0.812

0.593

3.65

8 Markers e

   

   Haplotypes

0.654

0.356

10.07

   Clusters

0.822

0.597

3.94

  1. aSex and number of DRB1*04 alleles were included as covariates in all analyses.
  2. bProportion of 1000 data sets of 150 each cases and controls giving p-values below nominal α.
  3. cMean degrees of freedom from the score test for association.
  4. dSNPs 3435–3440.
  5. eSNPs 3433, 3435–3441.
Back to article page

BMC Proceedings

ISSN: 1753-6561

Contact us