A graphical illustration for constructing agene-SNP intermixed network and a gene-gene network. In the graph, a red node represents a gene and a yellow node a SNP. a) A gene-SNP intermixed network. A SNP-gene pair is connected by either a solid or a dashed line. The dashed line denotes the scenario in which a SNP co-linker is in strong LD with other SNP(s) (e.g., SNP2 and SNP4); b) A gene-gene network extracted from the gene-SNP intermixed network. The number on a line shows the intensity of relationship between the two genes.