Table 3 Haplotype association resultsa
From: Comparison of tagging single-nucleotide polymorphism methods in association analyses
| Â | LRAP | HLA-DRB2 | CPNE1 | AA827892 | CSTB | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | p-set/dfb | min(p)c | p-set/df | min(p) | p-set/df | min(p) | p-set/df | min(p) | p-set/df | min(p) |
All SNPs | 1.8 × 10 -3 /5 d | 1.3 × 10 -5 | 1.6 × 10-2/3 | 5.1 × 10 -5 | 3.4 × 10 -3 /2 | 7.1 × 10 -5 | 2.1 × 10-1/2 | 1.8 × 10 -4 | 2.1 × 10 -4 /2 | 3.3 × 10 -4 |
ldSelect | 7.5 × 10 -4 /4 | 1.7 × 10 -4 | 8.5 × 10 -3 /4 | 5.1 × 10 -5 | 7.1 × 10 -5 /2 | 7.1 × 10 -5 | 5.2 × 10-2/2 | 5.2 × 10-2 | 1.8 × 10 -4 /2 | 2.3 × 10 -3 |
TagSNPs-Rspair | 1.4 × 10 -3 /5 | 3.9 × 10 -5 | 2.1 × 10-2/3 | 5.6 × 10 -5 | 7.1 × 10 -5 /2 | 7.1 × 10 -5 | 2.1 × 10-1/2 | 5.2 × 10-2 | 1.8 × 10 -4 /2 | 3.1 × 10 -3 |
TagSNPs-Rspair-trios | 1.4 × 10 -3 /5 | 3.9 × 10 -5 | 2.1 × 10-2/3 | 2.3 × 10 -4 | 7.1 × 10 -5 /2 | 7.1 × 10 -5 | 2.1 × 10-1/2 | 5.2 × 10-2 | 2.1 × 10 -4 /2 | 1.1 × 10 -3 |
Tagger-pairwise | 3.3 × 10 -4 /4 | 1.7 × 10 -5 | 9.5 × 10-3/4 | 5.1 × 10 -5 | 7.1 × 10 -5 /2 | 7.1 × 10 -5 | 5.2 × 10-2/2 | 5.2 × 10-2 | 1.8 × 10 -4 /2 | 3.0 × 10 -3 |
TagSNPs-Rs | 4.0 × 10 -4 /3 | 1.7 × 10 -4 | 4.1 × 10-2/3 | 1.5 × 10-5 | 1.1 × 10-4/2 | 1.1 × 10-4 | 1.7 × 10-1/2 | 1.7 × 10-1 | 5.0 × 10-1/4 | 2.7 × 10-2 |
TagSNPs-Rs-trios | 1.2 × 10 -3 /4 | 1.6 × 10 -4 | 1.3 × 10-3/4 | 5.7 × 10-4 | 7.1 × 10-5/2 | 7.1 × 10-5 | 1.7 × 10-1/2 | 1.7 × 10-1 | 5.0 × 10-1/4 | 2.7 × 10-2 |
Tagger-multimarker | 3.3 × 10 -4 /4 | 5.7 × 10 -5 | 1.7 × 10-2/3 | 5.7 × 10-5 | 7.1 × 10-5/2 | 7.1 × 10-5 | 5.2 × 10-2/2 | 5.2 × 10-2 | 1.8 × 10-4/2 | 1.3 × 10-3 |
TagSNPs-Rh | 8.7 × 10 -4 /4 | 2.0 × 10 -4 | 2.4 × 10-3/2 | 5.1 × 10-4 | 1.3 × 10-2/1 | 1.3 × 10-2 | 5.2 × 10-2/2 | 5.2 × 10-2 | 5.5 × 10-4/3 | 3.2 × 10-3 |
TagSNPs-Rh-trios | 6.4 × 10 -4 /3 | 1.4 × 10 -4 | 2.8 × 10-2/4 | 4.1 × 10-4 | 1.3 × 10-2/1 | 1.3 × 10-2 | 5.2 × 10-2/2 | 5.2 × 10-2 | 1.2 × 10-4/2 | 8.4 × 10-3 |