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Table 1 Master Regulators of Transcription (MRT)

From: Searching for master regulators of transcription in a human gene expression data set

Chr

cM

GO-ID

GO-Description

Regression

3

24

278

M phase of mitotic cell cycle

Yes

  

50684

regulation of mRNA processing

 

4

65

16740

Transferase activity

Yes

4

95

16932

Transferase activity, transferring glycosyl groups

 

6

44

30333

Antigen processing

 

6

 

45012

MHC class II receptor activity

 

7

142

5353

Fructose transporter activity

Yes

7

86

4324

Ferredoxin-NADP+ reductase activity

 

13

108

8240

Tripeptidyl-peptidase activity

Yes

14

93

16070

RNA metabolism

Yes

14

 

51252

Regulation of RNA metabolism

 

14

 

43283

Biopolymer metabolism

 

14

 

166

Nucleotide binding

 

20

54

4645

Phosphorylase activity

 

6

95

--

--

 

11

140

--

--

 
  1. The table shows the hot spots we found with the variance components method and the Gene Ontology (GO) over-represented terms for each of them. The last column indicates which hot spots were replicated with the feature selection regression method.