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Table 1 Master Regulators of Transcription (MRT)

From: Searching for master regulators of transcription in a human gene expression data set

Chr cM GO-ID GO-Description Regression
3 24 278 M phase of mitotic cell cycle Yes
   50684 regulation of mRNA processing  
4 65 16740 Transferase activity Yes
4 95 16932 Transferase activity, transferring glycosyl groups  
6 44 30333 Antigen processing  
6   45012 MHC class II receptor activity  
7 142 5353 Fructose transporter activity Yes
7 86 4324 Ferredoxin-NADP+ reductase activity  
13 108 8240 Tripeptidyl-peptidase activity Yes
14 93 16070 RNA metabolism Yes
14   51252 Regulation of RNA metabolism  
14   43283 Biopolymer metabolism  
14   166 Nucleotide binding  
20 54 4645 Phosphorylase activity  
6 95 -- --  
11 140 -- --  
  1. The table shows the hot spots we found with the variance components method and the Gene Ontology (GO) over-represented terms for each of them. The last column indicates which hot spots were replicated with the feature selection regression method.