Figure 2

Distribution of LOD scores when covariates are included in linkage analysis. Sex (A) or age (B) were included as covariates and are plotted on vertical axis, compared to no covariates on the horizontal axis. C, On the vertical axis age and generation were included as covariates, compared to age as a covariate on the horizontal axis. The solid line indicates symmetry, the dashed lines are at ±3 LOD scores from symmetry.