Identification of functional modules based on transcriptional regulation structure

BMC Proceedings

Table 1 GO-enrichment of the clusters obtained for S. Cerevisiae.

Cluster Id	GO BP Id	p-value	Cluster size	Biological process
6	0022613	1.28e – 23	80	ribonucleoprotein complex biogenesis and assembly
15	0006119	3.26e – 13	18	oxidative phosphorylation
9	0042254	3.15e – 11	55	ribosome biogenesis and assembly
4	0006081	4.89e – 07	142	aldehyde metabolic process
2	0000746	5.89e – 07	155	conjugation
7	0007001	9.48e – 07	68	chromosome organization and biogenesis (sensu Eukaryota)
13	0006974	4.10e – 05	30	response to DNA damage stimulus
27	0008652	2.02e – 04	6	amino acid biosynthetic process
10	0046907	3.50e – 04	52	intracellular transport
8	0019754	7.84e – 04	66	one-carbon compound catabolic process

Table of the ten best clusters among the 59 ones obtained for λ = 0.3 ranked by their best association with a GO term. For each of them, the best associated GO term and the corresponding p-value are given, as well as the size of the cluster and the biological process associated to the GO term.

ISSN: 1753-6561