Skip to main content

Table 1 Description and results from the 12 investigated regions

From: Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis

WTCCC studya

NARAC datab

Chr

SNP

Position

MAD of log10

Outlying SNPs, gene regions

log10 (BF)

RAF

λs Median (5th-95th)

   

GRRhom

GRRhet

    

1p13

rs6679677

11,401,850

0.282

0.199

rs2476601, PTPN22

3.91

0.084

1.048 (1.017-1.098)

1p36

rs6684865

2,578,391

0.282

0.199

-

-

-

-

1p31

rs11162922

80,284,079

0.282

0.199

-

-

-

-

4p15

rs3816587

25,093,513

0.255

0.188

rs12505556, SLC34A2

3.04

0.112

1.071 (1.011-1.630)

6p21a

rs6457617

32,771,829

0.306

0.206

rs2395175, MHC

16.48

0.148

1.164 (1.108-1.241)

     

rs7765379, MHC

6.11

0.113

1.175 (1.053-1.668)

6p21b

rs615672

32,682,149

0.306

0.206

rs2395175, MHC

16.48

0.148

1.164 (1.108-1.241)

     

rs7765379MHC

6.11

0.113

1.175 (1.053-1.668)

6q23

rs6920220

138,048,197

0.306

0.206

-

-

-

-

7q32

rs11761231

130,827,294

0.268

0.185

-

-

-

-

10p15

rs2104286

6,139,051

0.290

0.197

-

-

-

-

13q12

rs9550642

19,848,092

0.286

0.200

rs1407961, ZMYM2

3.59

0.920

1.033 (1.033-1.225)

21q22

rs2837960

41,433,788

0.288

0.208

rs468646, MX1

4.28

0.488

1.038 (1.019-1.057)

     

rs466092, MX2

3.59

0.488

1.030 (1.016-1.048)

22q13

rs743777

35,876,107

0.283

0.216

rs3218258, IL2RB

9.63

0.771

1.061 (1.041-1.084)

     

rs710183, CSF2RB

4.26

0.072

1.028 (1.011-1.183)

     

rs8137446, KCTD17

3.48

0.903

1.035 (1.018-1.123)

  1. aResults from the WTCCC study.
  2. bResults based on NARAC.
Back to article page

BMC Proceedings

ISSN: 1753-6561

Contact us