Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study

Table 1 p-Value for associated SNPs under the linkage peak (p < 0.0001 by PLINK or p < 0.001 by QTLD for one or more BMI measures)

SNP	Position (bp)	BMI-B		BMI1		BMI2		BMI3		BMI4		MEAN
		PLINK	QTLD	PLINK	QTLD	PLINK	QTLD	PLINK	QTLD	PLINK	QTLD	PLINK	QTLD
rs16945869 ^a	46732060	0.219	0.026	0.004	7.8 × 10 ^-6	0.006	0.0002	0.039	0.0006	0.001	10 ^-5	0.002	4.6 × 10 ^-6
rs11647781	48151920	0.002	0.0006	0.024	0.04	0.023	0.020	0.030	0.31	0.005	0.021	0.011	0.024
rs4785326	48173088	0.014	0.001	0.06	0.07	0.15	0.034	0.074	0.22	0.041	0.09	0.048	0.05
rs9939973	52358069	0.00014	0.010	0.019	0.18	0.002	0.06	0.001	0.016	0.00061	0.028	0.00044	0.012
rs9940128	52358255	0.00006	0.008	0.022	0.22	0.003	0.08	0.002	0.023	0.00051	0.028	0.00048	0.017
rs1121980	52366748	0.00016	0.011	0.023	0.22	0.002	0.09	0.002	0.025	0.00037	0.027	0.00035	0.017
rs7193144	52368187	0.00008	0.006	0.019	0.12	0.003	0.07	0.003	0.007	0.001	0.011	0.00074	0.006
rs8050136	52373776	0.00006	0.007	0.023	0.15	0.004	0.10	0.003	0.008	0.001	0.009	0.00069	0.007
rs9926289	52378004	0.00002	0.005	0.020	0.25	0.003	0.25	0.004	0.030	0.00086	0.023	0.00077	0.029
rs9939609	52378028	0.00002	0.008	0.018	0.15	0.003	0.12	0.002	0.010	0.001	0.013	0.00049	0.008

ISSN: 1753-6561