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Table 3 Percent of D' > 0.8 of 80 random samples of trios by sample size, compared to percent of D' > 0.8 for the 332 trios

From: Linkage disequilibrium of single-nucleotide polymorphism data: how sampling methods affect estimates of linkage disequilibrium

Distance bin (kb)

Range and mean ± SD

 
 

n= 25

n= 30

n= 40

n= 50

n= 100

n= 150

n= 200

n= 300

332 trios

0 - 5

90.5-91.9

89.7-91.1

90.0-91.1

89.9-91.1

89.8-91.2

90.0-91.2

90.1-91.1

90.5-91.1

90.7

 

91.3 ± 0.3

90.6 ± 0.3

90.5 ± 0.2

90.5 ± 0.3

90.6 ± 0.3

90.6 ± 0.2

90.7 ± 0.2

90.8 ± 0.1

 

5 - 10

80.6-82.0

78.9-80.4

79.1-80.3

79.1-80.6

79.0-80.2

79.1-80.3

79.3-80.2

79.3-80.1

79.6

 

81.5 ± 0.3

79.8 ± 0.3

79.6 ± 0.3

79.7 ± 0.3

79.7 ± 0.3

79.6 ± 0.2

79.7 ± 0.2

79.6 ± 0.2

 

10 - 15

74.3-75.6

71.6-73.3

71.7-73.2

71.5-73.1

71.6-73.0

71.5-73.1

71.6-72.6

71.4-72.3

71.9

 

74.9 ± 0.3

72.5 ± 0.4

72.3 ± 0.3

72.8 ± 0.3

72.3 ± 0.3

72.1 ± 0.3

72.1 ± 0.2

71.9 ± 0.1

 

15 - 20

68.9-70.5

65.7-67.6

65.7-67.1

65.4-67.3

65.6-67.1

65.6-66.8

65.8-66.7

65.9-66.5

66.2

 

68.9 ± 0.3

66.6 ± 0.4

66.3 ± 0.3

66.3 ± 0.3

66.3 ± 0.3

66.2 ± 0.3

66.3 ± 0.2

66.2 ± 0.1

 

20 - 25

64.0-65.5

60.3-62.1

60.2-61.4

60.1-61.5

59.8-61.5

60.0-61.5

59.6-61.4

60.7-61.4

61.1

 

64.6 ± 0.3

61.1 ± 0.3

60.8 ± 0.3

60.9 ± 0.3

60.7 ± 0.3

60.7 ± 0.3

60.6 ± 0.3

61.0 ± 0.1

 

25 - 30

59.7-61.4

56.0-57.4

55.6-57.0

55.6-57.2

55.6-57.0

55.7-57.3

55.5-56.8

56.1-56.9

56.6

 

60.4 ± 0.3

56.7 ± 0.4

56.3 ± 0.3

56.4 ± 0.4

56.3 ± 0.3

56.3 ± 0.3

56.3 ± ± 0.3

56.5 ± 0.1

 

30 - 40

54.5-56.0

50.1-51.5

49.7-51.1

49.8-51.4

49.6-50.9

49.7-51.1

49.9-51.2

50.2-51.0

50.6

 

55.3 ± 0.3

50.8 ± 0.3

50.4 ± 0.3

50.5 ± 0.3

50.4 ± 0.3

50.5 ± 0.2

50.5 ± 0.3

50.5 ± 0.2

 

40 - 50

49.3-50.9

44.1-45.6

43.4-45.4

43.9-45.2

43.8-45.2

43.8-45.2

43.6-45.1

44.1-45.0

44.5

 

49.9 ± 0.3

44.9 ± 0.3

44.4 ± 0.3

44.5 ± 0.3

44.4 ± 0.3

44.5 ± 0.3

44.3 ± 0.3

44.5 ± 0.2

 

50 - 60

45.5-47.3

39.9-41.4

39.5-41.0

39.5-41.2

39.5-40.9

39.6-41.0

39.6-40.7

39.8-40.5

40.2

 

46.4 ± 0.4

40.6 ± 0.3

40.1 ± 0.3

40.2 ± 0.3

40.1 ± 0.3

40.2 ± 0.3

40.1 ± 0.3

40.2 ± 0.1

 

60 - 70

42.4-44.1

36.5-37.8

36.1-37.4

35.9-37.3

35.7-37.3

35.9-37.5

36.0-37.2

362-37.1

36.9

 

43.2 ± 0.3

37.2 ± 0.3

36.60.3

36.6 ± 0.3

36.6 ± 0.3

36.6 ± 0.3

36.6 ± 0.3

36.7 ± 0.2

 

70 - 80

39.7-41.3

33.1-34.6

32.9-34.0

32.7-34.1

32.7-34.0

32.7-34.1

32.9-34.1

33.1-33.9

33.6

 

40.3 ± 0.4

33.9 ± 0.3

33.4 ± 0.3

33.4 ± 0.3

33.4 ± 0.3

33.5 ± 0.3

33.5 ± 0.2

33.6 ± 0.1

 

80 - 90

37.5-39.5

31.1-32.9

30.7-32.0

30.5-32.4

30.6-31.7

30.7-31.8

30.7-31.8

30.8-31.7

31.2

 

38.4 ± 0.4

31.8 ± 0.4

31.2 ± 0.3

31.3 ± 0.4

31.1 ± 0.3

31.2 ± 0.3

31.2 ± 0.2

31.1 ± 0.2

 

90 - 100

35.4-37.4

28.7-30.4

28.2-29.7

28.2-30.1

28.0-29.5

28.2-29.7

28.3-29.4

28.5-29.2

28.8

 

36.4 ± 0.4

29.5 ± 0.4

28.9 ± 0.3

29.0 ± 0.4

28.9 ± 0.3

28.8 ± 0.3

28.8 ± 0.2

28.8 ± 0.1

 

100 - 140

32.3-34.1

25.3-26.4

24.6-25.8

24.7-25.9

24.7-25.7

24.6-25.8

24.9-25.9

25.3-25.9

25.7

 

33.1 ± 0.4

25.9 ± 0.3

25.3 ± 0.2

25.3 ± 0.3

25.2 ± 0.2

25.3 ± 0.2

25.4 ± 0.2

25.6 ± 0.1

 

140 - 180

28.8-30.5

21.5-22.7

21.0-21.8

20.8-22.0

20.9-21.7

20.8-22.0

20.8-21.8

21.1-21.7

21.4

 

29.7 ± 0.4

22.1 ± 0.2

21.4 ± 0.2

21.4 ± 0.3

21.3 ± 0.2

21.4 ± 0.2

21.4 ± 0.2

21.4 ± 0.1

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