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Table 4 Percent of D' > 0.8 of 80 random samples of independent individuals by sample size, compared to percent of D' > 0.8 for the 332 trios

From: Linkage disequilibrium of single-nucleotide polymorphism data: how sampling methods affect estimates of linkage disequilibrium

Distance bin (kb)

Range and mean ± SD

 
 

n= 25

n= 30

n= 40

n= 50

n= 100

n= 150

n= 200

n= 300

332 trios

0 - 5

88.4-89.5

88.1-89.2

87.5-88.6

86.6-88.3

85.0-86.9

85.8-86.8

85.9-86.6

86.1-86.8

90.7

 

89.0 ± 0.3

88.6 ± 0.3

88.1 ± 0.3

87.8 ± 0.4

86.1 ± 0.4

86.2 ± 0.4

86.3 ± 0.1

86.6 ± 0.1

 

5 - 10

80.3-81.9

79.2-81.1

78.5-80.0

77.7-79.6

74.5-76.6

74.6-75.8

74.6-75.3

74.7-75.3

79.6

 

81.0 ± 0.3

80.3 ± 0.3

79.3 ± 0.3

78.7 ± 0.4

75.7 ± 0.5

75.2 ± 0.5

75.0 ± 0.2

75.0 ± 0.1

 

10 - 15

75.3-76.7

74.3-75.8

72.9-74.4

71.9-73.7

67.9-69.9

67.4-68.5

67.1-67.9

67.1-76.7

71.9

 

76.0 ± 0.3

75.1 ± 0.3

73.7 ± 0.3

73.0 ± 0.4

69.0 ± 0.5

67.9 ± 0.6

67.6 ± 0.2

67.3 ± 0.1

 

15 - 20

71.2-72.8

70.1-71.5

68.5-69.8

67.1-69.1

61.8-64.1

61.5-62.4

61.0-61.9

60.7-61.2

66.2

 

72.0 ± 0.3

70.8 ± 0.3

69.2 ± 0.3

68.1 ± 0.4

63.0 ± 0.5

62.0 ± 0.5

61.4 ± 0.2

60.9 ± 0.1

 

20 - 25

67.4-69.1

65.8-67.9

63.9-65.3

62.8-64.6

57.1-58.8

55.6-56.9

54.9-56.1

54.4-55.0

61.1

 

68.1 ± 0.3

66.6 ± 0.3

64.7 ± 0.3

63.6 ± 0.3

58.0 ± 0.5

56.2 ± 0.6

55.5 ± 0.2

54.8 ± 0.1

 

25 - 30

64.0-65.7

62.2-64.3

60.2-61.8

58.9-61.1

52.6-54.7

51.4-52.4

50.7-51.6

50.2-50.8

56.6

 

64.8 ± 0.4

63.2 ± 0.4

61.1 ± 0.3

59.8 ± 0.4

53.7 ± 0.5

51.9 ± 0.7

51.1 ± 0.2

50.5 ± 0.1

 

30 - 40

60.4-61.9

58.6-60.1

56.3-57.5

54.8-57.0

47.4-49.3

45.7-46.9

44.9-45.7

43.9-44.3

50.6

 

61.0 ± 0.3

59.2 ± 0.3

56.9 ± 0.3

55.5 ± 0.4

48.5 ± 0.4

46.3 ± 0.5

45.2 ± 0.2

44.1 ± 0.1

 

40 - 50

56.5-58.3

54.5-56.2

51.8-53.3

49.9-52.6

41.8-43.6

39.6-40.7

38.5-39.4

37.3-37.7

44.5

 

57.2 ± 0.3

55.2 ± 0.3

52.4 ± 0.3

50.8 ± 0.5

42.9 ± 0.3

40.1 ± 0.5

38.9 ± 0.2

37.5 ± 0.1

 

50 - 60

53.7-55.4

51.6-53.3

48.7-50.3

46.9-49.4

38.1-39.5

35.7-36.8

34.4-35.3

33.0-33.5

40.2

 

54.5 ± 0.4

52.4 ± 0.3

49.5 ± 0.3

47.7 ± 0.5

39.0 ± 0.3

36.2 ± 0.5

34.7 ± 0.2

33.2 ± 0.1

 

60 - 70

51.4-53.1

49.2-53.0

46.1-47.7

44.3-46.7

35.1-36.2

32.1-33.3

30.6-31.5

29.2-29.7

36.9

 

52.3 ± 0.3

50.1 ± 0.3

46.9 ± 0.3

45.1 ± 0.6

35.8 ± 0.2

32.7 ± 0.4

31.1 ± 0.2

29.4 ± 0.1

 

70 - 80

49.5-51.4

47.0-48.9

43.8-45.5

41.6-44.9

32.4-33.6

29.1-30.1

27.4-28.2

25.7-26.3

33.6

 

50.3 ± 0.4

47.9 ± 0.4

44.7 ± 0.4

42.7 ± 0.7

33.0 ± 0.3

29.5 ± 0.4

27.8 ± 0.2

26.0 ± 0.1

 

80 - 90

48.1-49.9

45.7-47.4

42.2-43.9

40.1-43.5

30.3-31.6

26.9-27.9

25.1-26.0

23.4-23.8

31.2

 

49.0 ± 0.4

46.5 ± 0.4

43.1 ± 0.4

41.2 ± 0.7

31.0 ± 0.3

27.4 ± 0.4

25.5 ± 0.2

23.6 ± 0.1

 

90 - 100

46.8-48.5

44.2-45.8

40.5-42.2

38.1-41.8

28.1-29.4

24.7-25.4

22.6-23.4

20.7-21.3

28.8

 

47.6 ± 0.4

45.0 ± 0.4

41.4 ± 0.4

39.3 ± 0.8

28.8 ± 0.3

25.0 ± 0.5

23.0 ± 0.2

20.9 ± 0.1

 

100 - 140

44.6-46.1

42.0-43.5

38.0-39.6

35.3-39.1

24.9-26.1

21.2-22.0

19.2-19.9

17.0-17.3

25.7

 

45.3 ± 0.3

42.6 ± 0.3

38.8 ± 0.4

36.6 ± 0.8

25.5 ± 0.2

21.6 ± 0.3

19.5 ± 0.1

17.2 ± 0.1

 

140 - 180

42.0-43.9

39.1-41.1

35.2-37.0

32.7-36.9

21.4-22.8

17.5-18.2

15.3-15.9

13.0-13.4

21.4

 

43.0 ± 0.4

40.1 ± 0.4

36.2 ± 0.4

33.8 ± 0.9

22.1 ± 0.3

17.8 ± 0.3

15.6 ± 0.1

13.2 ± 0.1

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