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Table 2 Characteristics of the intercepts and slopes from the growth curve modelsa

From: Genome-wide association analysis of cardiovascular-related quantitative traits in the Framingham Heart Study

  BMI time-invariantb BMI time-varyingc
Trait Intercept Slope Slope/intercept ratio (%) Intercept Slope Slope/intercept ratio (%)
HDL 51.6 ± 10.9 0.37 ± 2.20 0.72 74.9 ± 9.9 1.75 ± 2.24 2.33
LDL 126.4 ± 29.0 1.36 ± 5.66 1.07 85.6 ± 28.2 7.85 ± 5.18 9.17
TG 83.2 ± 50.7 20.86 ± 20.41 25.03 -16.4 ± 48.8 12.31 ± 20.97 74.92
SBP 120.3 ± 10.8 3.08 ± 3.31 2.56 93.5 ± 9.2 0.09 ± 3.25 0.10
  1. aValues are mean ± standard deviation. Units are mg/dL for HDL, LDL, and TG intercept; mm Hg for SBP intercept; mg/dL per visit for HDL, LDL, and TG slope; mm Hg per visit for SBP intercept.
  2. bModel included sex, baseline age, diabetes status, and baseline BMI as time-invariant covariates, and number of cigarettes smoked per day as a time-varying covariate.
  3. cModel identical to BMI time-invariant model, except BMI was treated as a time-varying covariate.