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Table 2 Characteristics of the intercepts and slopes from the growth curve modelsa

From: Genome-wide association analysis of cardiovascular-related quantitative traits in the Framingham Heart Study

 

BMI time-invariantb

BMI time-varyingc

Trait

Intercept

Slope

Slope/intercept ratio (%)

Intercept

Slope

Slope/intercept ratio (%)

HDL

51.6 ± 10.9

0.37 ± 2.20

0.72

74.9 ± 9.9

1.75 ± 2.24

2.33

LDL

126.4 ± 29.0

1.36 ± 5.66

1.07

85.6 ± 28.2

7.85 ± 5.18

9.17

TG

83.2 ± 50.7

20.86 ± 20.41

25.03

-16.4 ± 48.8

12.31 ± 20.97

74.92

SBP

120.3 ± 10.8

3.08 ± 3.31

2.56

93.5 ± 9.2

0.09 ± 3.25

0.10

  1. aValues are mean ± standard deviation. Units are mg/dL for HDL, LDL, and TG intercept; mm Hg for SBP intercept; mg/dL per visit for HDL, LDL, and TG slope; mm Hg per visit for SBP intercept.
  2. bModel included sex, baseline age, diabetes status, and baseline BMI as time-invariant covariates, and number of cigarettes smoked per day as a time-varying covariate.
  3. cModel identical to BMI time-invariant model, except BMI was treated as a time-varying covariate.