Table 1 The Scheffe grouping and the mean of 
for the five SNPs that determine CAC
for the five SNPs that determine CACFrom: Family-based analysis of a myocardial infarction endophenotype: comparison of sampling designs
SNP | Genetic variancea | Scheffe grouping | Mean (+/-)b | Sampling design |
|---|---|---|---|---|
Ï„ 1 | Â | A | 0.87+ | CAC |
| Â | Â | B | 0.43+ | MI |
| Â | 0 | C | 0.05 | Random |
Ï„2 | Â | A | 0.64 | CAC |
| Â | Â | A | 0.71+ | MI |
| Â | 1,250 | B | 0.01 | Random |
Ï„3 | Â | B | 0.35 | CAC |
| Â | Â | A | 0.76+ | MI |
| Â | 0 | C | 0.03 | Random |
Ï„4 | Â | B | 0.58 | CAC |
| Â | Â | B | 0.60+ | MI |
| Â | 0 | A | 1.09+ | Random |
Ï„5 | Â | B | 0.48 | CAC |
| Â | Â | C | 0.24+ | MI |
| Â | 10,000 | A | 1.33+ | Random |
Ï„1 Ï„2 epistasis | Â | B | 0.13 | CAC |
| Â | Â | A | 0.28 | MI |
| Â | 20,000 | B | 0.09 | Random |
Ï„3 Ï„4 epistasis | Â | A | 1.82+ | CAC |
| Â | Â | A | 1.85+ | MI |
| Â | 40,000 | B | 0.39 | Random |
- aUsing the mean genetic effects and the population allele frequencies given in Kraja et al [4]. b(+/-): Above (+), below (-), or on () the 95% empirical prediction interval for the average .