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Table 1 Test results of the 5 SNPs from 500 k panel for major gene effects of HDL

From: Family-based genome-wide association study for simulated data of Framingham Heart Study

Model

Location

Intercept

Diet

Sex

Rxa

Age

Smokeb

SNP

SE

p-Value

rs10820738

9q31.1

68.694

0.028

13.565

1.486

0.019

0.714

4.524

0.518

3.20 × 10-18

rs3200218

8p22

68.680

0.027

13.552

1.420

0.020

0.664

-1.671

0.319

1.63 × 10-7

rs8035006

15q21

68.684

0.023

13.527

1.474

0.020

0.647

0.831

0.284

0.003

rs8192719

19q13.2

68.689

0.021

13.524

1.470

0.020

0.666

-0.821

0.306

0.007

rs8103444

19113.2

68.686

0.021

13.533

1.452

0.019

0.660

0.629

0.305

0.039

  1. aRx, lipid lowering drug use
  2. bSmoke, smoking status