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Table 3 Top-ranked genes associated with RA on chromosome 6

From: Gene hunting of the Genetic Analysis Workshop 16 rheumatoid arthritis data using rough set theory

Gene symbol

No. SNPsa

SCb

p-Valuec

HLA-DRB1

6/6

1.00

4.89 × 10-114

HLA-DRA

10/10

0.90

1.18 × 10-86

BTNL2

10/10

0.36

6.86 × 10-81

HLA-DQB1

8/10

0.36

1.86 × 10-77

HLA-DQA2

10/10

1.00

6.19 × 10-74

HLA-DQA1

5/5

1.00

2.78 × 10-72

C6orf10

10/10

0.88

9.01 × 10-70

LOC401252

9/10

0.82

7.15 × 10-51

HLA-DOB

10/10

1.00

8.00 × 10-32

  1. aThe number of selected SNPs and the total number of SNPs that were genotyped.
  2. bSC, stability coefficient.
  3. cThe adjusted p-values (no clustering) for all genes in the table are less than 0.001 (1,000 permutations). No clustering was performed.