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Table 2 Distribution of selected genes and SNPs in each of the two regions and nine gene sets/pathways

From: Pathway-based analysis of a genome-wide case-control association study of rheumatoid arthritis

 

MHC region

(Chr 6, 29-34 Mba)

Rest of genome

Gene sets/pathways

No. genes

%b

#SNPs

No. genes

%a

No. SNPs

Hsa04612 antigen processing and Presentation

24

42.1

5

33

57.9

0

Hsa04940 Type I Diabetes Mellitus

22

55.0

6

18

45.0

0

Wieland hepatitis B-iInduced

15

17.2

4

72

82.8

0

Ctla4 pathway

2

11.1

0

16

88.9

1

Ami pathway

2

9.1

0

20

90.9

0

Csk pathway

2

9.1

0

20

90.9

0

Sana Ifng endothelial up

11

16.4

2

56

83.6

0

Th1th2 pathway

2

11.8

0

15

88.2

0

Inflam pathway

4

14.3

2

24

85.7

0

Hsa04514 cell adhesion molecule

20

17.4

5

95

82.6

1

  1. aThis region covers approximately 0.2% the whole genome
  2. bThe percentage of genes in a given gene set that were found in the region