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Table 2 HLA region association with rheumatoid arthritis and arthritis-related traits

From: A principal-components-based clustering method to identify multiple variants associated with rheumatoid arthritis and arthritis-related autoantibodies

  

RA affection status

Anti-CCP

RFUW

Method

df

χ2 Statistica

p-Value

χ2 Statistica

p-Value

χ2 Statistica

p-Value

Traditional PC analysis

53

556.274

4.8 × 10-85

49.28

0.6197

77.432

0.0159

PC-based cluster analysis

188

789.007

1.4 × 10-74

203.383

0.2098

297.838

5.7 × 10-7

  1. aχ2 statistic based on multi-df likelihood ratio test for number of PCs or clusters included in the full model vs. the null model (intercept only).