Table 1 Genomic regions and candidate genes identified for case-control study of rheumatoid arthritis in GAW16
Chromosome | Genomic region (Mb) | SNP with the largest effect | Number of genes | Candidate genes |
|---|---|---|---|---|
6p21.33 | 31.55-31.62 | rs2523647 | 4 | MICB-001; MICB-002; MCCD1-001; BAT1 |
6p21.32 | 32.33-32.41 | rs10484560 | 1 | C6orf10 |
6p21.32 | 32.47-32.69 | rs3135363 | 6 | BTNL2; HLA-DRA; AL662796.6; HLA-DRB9; HLA-DRB5; HLA-DRB1 |
6p21.32 | 37.74-32.79 | rs9275601 | 1 | HLA-DQB1 |
6p21.32 | 32.87-32.97 | rs9380326 | 5 | HLA-DOB; TAP2; PSMB8; PSMB9; TAP1 |
6p21.32 | 33.21-33.29 | rs3130237 rs6901221 | 5 | COL11A2; RXRB; SLC39A7; HSD17B8; RING1 |
9q33.1 | 12.05-12.12 | rs2900180 | 3 | DBC1; TRAF1a; C5a |
10q11.22 | 49.64-49.79 | rs2671692 | 2 | C10orf64; LRRC18 |
18q12.1 | 26.82-26.88 | rs2852003 | 1 | DSC3 |