Comparison of a unified analysis approach for family and unrelated samples with the transmission-disequilibrium test to study associations of hypertension in the Framingham Heart Study

Table 1 Inflation factor and type I error for FamCC and FBAT

Method	Sample	Inflation factor λ			Type I error (0.05 level)^a
		Hypertension	SBP	DBP	Hypertension	SBP	DBP
FamCC	Unrelated subsample	1.03	1.01	1.02	0.053	0.049	0.051
FamCC	Family sample	1.06	1.03	1	0.048	0.051	0.051
FBAT	Family sample	1.00	0.98	1.02	0.051	0.046	0.055

ISSN: 1753-6561