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Table 1 Significant associations detected by GAB algorithm

From: Genome-wide association studies using single-nucleotide polymorphisms versus haplotypes: an empirical comparison with data from the North American Rheumatoid Arthritis Consortium

Chr Start position End position p-value Include significant SNPsa Overlap with significant GAM blocksb
1 1,045,729 1,058,627 1.67 × 10-14 Yes Yes
1 55,680,975 55,682,288 2.42 × 10-8 Yes No
1 150,433,159 150,471,553 1.26 × 10-8 No Yes
1 22,244,528 22,251,559 4.01 × 10-10 No No
3 58,921,915 59,057,595 6.27 × 10-11 Yes Yes
3 108,502,403 108,548,227 2.28 × 10-11 No Yes
3 156,354,381 156,381,109 1.26 × 10-7 No Yes
4 36,082,845 36,105,879 5.76 × 10-8 No No
5 38,767,613 38,785,799 6.62 × 10-8 No No
5 127,305,116 127,355,548 2.69 × 10-7 No No
5 137,669,365 137,669,929 2.67 × 10-8 Yes No
5 168,125,453 168,128,612 1.54 × 10-7 No Yes
7 26,122,453 26,143,430 6.70 × 10-9 No No
7 129,556,365 129,578,739 4.97 × 10-12 Yes No
7 137,469,416 137,478,601 4.64 × 10-8 No No
8 20,619,747 20,619,773 4.41 × 10-8 No Yes
8 22,942,075 22,948,219 7.39 × 10-10 No No
8 144,734,804 144,746,191 1.31 × 10-8 No Yes
9 81,662,684 81,666,969 4.29 × 10-8 Yes Yes
10 48,046,897 48,050,873 2.60 × 10-11 No No
10 71,263,263 71,264,307 9.28 × 10-11 No Yes
10 92,582,936 92,663,587 1.05 × 10-37 No Yes
10 96,750,802 96,788,739 2.66 × 10-11 No No
10 99,590,357 99,601,703 2.41 × 10-7 No No
11 44,243,624 44,243,868 2.12 × 10-10 No No
11 1,274,888 1,313,639 2.20 × 10-9 No No
12 11,438,799 11,477,909 2.44 × 10-7 No Yes
13 113,781,019 113,839,177 3.73 × 10-12 Yes No
14 80,904,425 80,935,179 4.93 × 10-9 No Yes
14 104,491,260 104,507,267 1.15 × 10-9 No No
14 29,207,158 29,246,917 2.97 × 10-10 No No
15 65,048,226 65,074,484 1.42 × 10-12 No Yes
15 87,225,585 87,243,610 1.71 × 10-12 No Yes
16 1,478,364 1,484,303 2.01 × 10-8 No Yes
16 11,827,538 11,924,420 4.24 × 10-10 No No
16 12,089,203 12,101,855 6.25 × 10-10 No No
17 67,936,240 67,937,413 6.62 × 10-9 No Yes
17 17,997,997 18,077,866 2.87 × 10-9 No No
19 39,820,387 39,827,349 2.35 × 10-8 No No
19 46,151,081 46,152,461 3.26 × 10-8 No No
19 51,106,074 51,111,613 8.85 × 10-8 No No
19 61,351,554 61,371,582 5.88 × 10-11 No Yes
19 13,193,010 13,196,432 9.92 × 10-11 No Yes
19 18,085,729 18,093,754 1.928 × 10-7 No Yes
19 2,051,346 2,074,516 2.47 × 10-7 No Yes
19 2,957,274 2,966,481 1.90 × 10-11 No Yes
22 38,301,711 38,309,783 2.62 × 10-7 No Yes
22 42,547,708 42,605,295 1.11 × 10-13 No Yes
22 49,370,904 49,400,136 2.93 × 10-8 Yes Yes
22 28,201,971 28,202,179 8.14 × 10-12 No No
22 35,868,745 35,875,810 5.28 × 10-8 No No
  1. aInclude SNPs which are significant in individual SNP association test
  2. bOverlap with blocks which are constructed by four gamete rule and significant in a haplotype association test.