Table 1 Search results for best single and multiple SNP associations with T2D status
Method | Gene | Chr | Position | RAFa | Bayes Factor | Rank | P b |
|---|---|---|---|---|---|---|---|
BIMBAM | |||||||
rs10811661 | CDKN2A/2B | 9p | 22124094 | T, 0.82 | 0.978 | 1 | 0.0045 |
rs4506565 | TCF7L2 | 10q | 114748339 | T, 0.36 | 0.591 | 2 | 0.0154 |
rs864745 | JAZF1 | 7p | 28147081 | A, 0.52 | 0.041 | 3 | 0.0397 |
rs17030946 | THADA | 2p | 43587013 | T, 0.10 | 0.035 | 4 | 0.0771 |
rs7961581 | TSPAN8-LGR5 | 12q | 69949369 | T, 0.70 | -0.161 | 5 | 0.1298 |
rs10946398 | CDKAL1 | 6p | 20769013 | C, 0.33 | -0.284 | 6 | 0.2382 |
rs5215 | KCNJ11 | 11p | 17365206 | C, 0.36 | -0.292 | 7 | 0.0944 |
rs2793823 | ADAM30 | 1p | 120239241 | G, 0.89 | -0.366 | 8 | 0.4292 |
rs10282940 | SLC30A8 | 8q | 118257007 | G, 0.89 | -0.381 | 9 | 0.4606 |
rs5018648 | WFS1 | 4p | 6343719 | G, 0.61 | -0.457 | 10 | 0.2901 |
rs8050136 | FTO | 16q | 52373776 | A, 0.41 | -0.457 | 11 | 0.4008 |
rs1801282 | PPARG | 3p | 12368125 | G, 0.11 | -0.488 | 12 | 0.8047 |
rs564398 | CDKN2A/2B | 9p | 22019547 | G, 0.39 | -0.517 | 13 | 0.5119 |
rs4402960 | IGF2BP2 | 3q | 186994381 | G, 0.67 | -0.601 | 14 | 0.4523 |
rs4607103 | ADAMTS9 | 3p | 64686944 | C, 0.74 | -0.613 | 15 | 0.8136 |
SNP pair 1 | -- | -- | -- | -- | 1.76 | 1, 2 | -- |
SNP pair 2 | -- | -- | -- | -- | 1.064 | 1, 3 | -- |
LOGREG | Gene | Chr | Position | RAF | Beta | Mode c | Logic |
rs864745 | JAZF1 | 7p | 28147081 | A, 0.52 | 0.03 (tree 1) | Rec | and |
rs10811661 | CDKN2A/2B | 9p | 22124094 | T, 0.82 | 0.09 (tree 2) | Rec | and |
rs4506565 | TCF7L2 | 10q | 114748339 | T, 0.36 | 0.09 (tree 2) | Dom | and |
rs5215 | KCNJ11 | 11p | 17365206 | C, 0.36 | 0.09 (tree 2) | Dom | or |