A two-stage search strategy for detecting multiple loci associated with rheumatoid arthritis

BMC Proceedings

Table 2 {SNP;C} interactions with KWII values ≥ 95^th percentile of the 1-variable KWII obtained for Data Set 1, Data Set 2, Data Set 3

SNP	Gene/genome region	KWII	p-Value^b
Data Set 1: = 0.015^a
rs2395175	HLA-DR	0.195	0
rs660895	6p21.3	0.189	0
rs6910071	6p21.3	0.163	0
rs3763312	6p21.3	0.151	0
Data Set 2: = 0.075
rs2395175	HLA-DR	0.195	0
rs7192	HLA-DR	0.094	0
rs3129871	HLA-DR	0.079	0
rs3129882	HLA-DR	0.075	0
Data Set 3: = 0.02
rs731059	RUNX1	0.048	0
rs475142	RUNX1	0.024	1.3 × 10^-11

^a denotes the 95^th percentile KWII for combinations of order i and Data Set j.
^b p-Value obtained using logistic regression

ISSN: 1753-6561