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Table 4 The two-variable interactions with KWII values ≥ 95th percentile (0.01) obtained using SNPs on gene × gene pairs on Data Set 1

From: A two-stage search strategy for detecting multiple loci associated with rheumatoid arthritis

SNP1-SNP2

Gene/genome region 1 - Gene/genome region 2

KWII

p-Valuea

rs9275596-rs1542876

6p21.3-RUNX1

0.01914

2.05 × 10-6

rs2856725-rs1542876

6p21.3-RUNX1

0.01743

3.61 × 10-5

rs9275596-rs1041778

6p21.3-RUNX1

0.01471

8.25 × 10-7

rs7770216-rs563495

6p21.3-6q23

0.01444

4.15 × 10-7

rs7755852-rs2745443

6p21.3-6q23

0.01275

6.22 × 10-7

rs9275698-rs1883468

6p21.3-6q23

0.01262

4.51 × 10-7

rs4673260-rs12190331

CTLA4-6q23

0.01385

7.86 × 10-8

rs1206684-rs651084

6q23-RUNX1

0.01261

6.12 × 10-5

rs2844729-rs16984549

6p21.3-RUNX1

0.01255

5.71 × 10-7

rs2856725-rs1041778

6p21.3-RUNX1

0.01247

6.54 × 10-6

  1. a p-Value obtained using logistic regression.