Rheumatoid arthritis-associated gene-gene interaction network for rheumatoid arthritis candidate genes

BMC Proceedings

Table 1 RA candidate genes

Gene	Gene Set I	Gene Set II	Locus	SNPs
PTPN22	Yes	Yes	1p13	12
PADI4	Yes	Yes	1p36.13	18
FCRL3	Yes	No	1q21.2-q22	8
FCGR3	Yes	Yes	1q23	4
IL10	Yes	No	1q31-q32	16
TNFRSF1B	Yes	Yes	1p36.3-p36.2	21
IL1B	Yes	Yes	2q14	7
ITGAV	Yes	Yes	2q31	16
STAT4	Yes	Yes	2q32.2-q32.3	30
CTLA4	Yes	Yes	2q33	5
BTLA	Yes	Yes	3q13.2	6
SLC22A4	Yes	Yes	5q31	19
IL13	No	Yes	5q31	6
IL3	Yes	Yes	5q31.1	3
IL4	Yes	No	5q31.1	7
HAVCR1	Yes	No	5q33.2	15
VEGF	Yes	Yes	6p12	12
HLADRB1	Yes	Yes	6p21.3	5
MICA	Yes	No	6p21.3	32
HLA-A	No	Yes	6p21.3	6
HLA-B	No	Yes	6p21.3	24
HLA-C	No	Yes	6p21.3	29
LTA	No	Yes	6p21.3	11
NFKBIL1	Yes	Yes	6p21.3	19
TNF	Yes	Yes	6p21.3	10
OLIG3 - TNFAIP3	Yes	No	6q23	76
IL6	No	Yes	7q21	14
TRAF1-C5	Yes	Yes	9q33-q34	31
DLG5	Yes	No	10q23	17
MS4A1	No	Yes	11q31	13
MHC2TA	Yes	No	16p13	12
CARD15	Yes	No	16q12	11
RUNX1	Yes	No	21q22.3	104
MIF	Yes	Yes	22q11.2	15

ISSN: 1753-6561