Table 3 Genes containing ≥ 1 SNPs with "pure" SNP × TIC interactions for CHD (α = 10-5), and p-values for most significant SNPs and their MAFs
Chr | MAF | Gene | TIC1 | TIC2 | TIC3 | TIC4 | No. significant SNPs |
|---|---|---|---|---|---|---|---|
1 | 0.052 | TNNI3K | 1.59 × 10-6 | 1 | |||
3 | 0.113 | CNBP | 8.73 × 10-6 | 3 | |||
4 | 0.060 | PCDH7 | 4.76 × 10-7 | 1 | |||
5 | 0.066 | PARP8 | 8.27 × 10-6 | 1 | |||
6 | 0.160 | TRDN | 3.83 × 10-6 | 3 | |||
8 | 0.237 | EIF3H | 1.78 × 10-6 | 2 | |||
8 | 0.158 | SGCZ | 2.25 × 10-6 | 1 | |||
9 | 0.085 | FREQ | 4.58 × 10-6 | 1 | |||
10 | 0.053 | FAS | 1.16 × 10-7 | 1 | |||
15 | 0.061 | GABRG3 | 3.00 × 10-6 | 1 | |||
15 | 0.085 | TJP1 | 6.01 × 10-6 | 2 | |||
16 | 0.313 | ARHGAP17 | 9.18 × 10-6 | 2 |