Skip to main content
Download PDF

Volume 5 Supplement 1

Institut Pasteur International Network Annual Scientific Meeting

  • Poster presentation
  • Open access
  • Published:

Hantavirus infection in human and rodents in central highlands and southern Vietnam during 2006-2009

BMC Proceedings volume 5, Article number: P55 (2011) Cite this article

From 2006 to 2009, a surveillance of the situation of hantavirus infection in Southern part and Highlands of Vietnam was carried out based on the tested results of serum samples from 1,066 rodents representing 6 species and 245 Suncus murinus.

The results of tested rodent sera samples by ELISA, IFA and confirmed by Western Blot showed that the prevalence antibody to hantavirus was 16.76% from R.norvegicus, and 13.1% from S.murinus. The serotyping result by FRNT revealed that hantaviruses which circulate in Southern Vietnam belong to Seoul and TPMV serotype. RNA of hantavirus was detected from 3 lung tissues of Rattus norvegicus samples which are coded as CSG5, CSG11 and 24D12, all collected in Ho Chi Minh City (Sai Gon Habor and District 12). The sequencing and phylogenetic analysis on detected genes (partial small and medium segments) demonstrated the close genetic relationship with SEOV representatives found in Japan, Indonesia Singapore and Northern Vietnam.

The serological analysis revealed the circulation of hantavirus including Seoul virus (SEOV) from Rattus.sp, and Thottopalayam virus from S. murinus in Southern and Highlands of Vietnam. Besides, the detection of specific IgM and the neutralizing antibody against SEOV in patient indicated the first evidence of the circulation and transmission of SEOV from rodent to human.

Author information

Authors and Affiliations

  1. Department of Microbiology and Immunology, Pasteur Institute of Ho Chi, Minh City, Vietnam

    Vu Thi Que Huong, Vu Dinh Luan, Le Nhi, Cao Minh Thang & Hoang Kim Loan

  2. Department of Virology, Tay Nguyen Institute of Hygiene and Epidemiology, Dak Lak Province, Vietnam

    Vo Thi Huong

  3. Institute for Animal Experimentation, Graduate School of Medicine, Hokkaido University, Japan

    Kumiko Yoshimatsu, Midori Taruishi, Endo Rika & Jiro Arikawa

Authors
  1. Vu Thi Que Huong
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Vu Dinh Luan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kumiko Yoshimatsu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Midori Taruishi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Le Nhi
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Endo Rika
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Vo Thi Huong
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Cao Minh Thang
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Hoang Kim Loan
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Jiro Arikawa
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vu Thi Que Huong.

Rights and permissions

This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Reprints and permissions

About this article

Cite this article

Huong, V.T.Q., Luan, V.D., Yoshimatsu, K. et al. Hantavirus infection in human and rodents in central highlands and southern Vietnam during 2006-2009. BMC Proc 5 (Suppl 1), P55 (2011). https://doi.org/10.1186/1753-6561-5-S1-P55

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/1753-6561-5-S1-P55

Keywords

BMC Proceedings

ISSN: 1753-6561

Contact us