Figure 7

CIM containing nlz2 Clustered Image Map (produced by GoMiner) showing enriched functional categories for the cluster that contains nlz2 and 168 other genes. More genes in this cluster have been associated to the 5 above GO categories (gene silencing is among them) than one would expect by chance. The 7 genes (DNMT1,…,TOPBP1) above are mapped to these GO categories within the GoMiner database. Red indicates that genes were mapped to GO categories. Yellow means no annotation. Due to gene expression co-variation within the cluster, other genes in the cluster could possibly related to the above GO categories too. Since gene silencing is associated to this cluster, one may speculate that nlz2 and co-varying genes have repressive function and that there is a cluster that shows the reverse expression profile, see Figure 8.