Health-care associated infection in Africa
© Nejad et al; licensee BioMed Central Ltd. 2011
Published: 29 June 2011
Introduction / objectives
To assess the epidemiology of endemic health care-associated infection (HAI) in Africa.
We searched biomedical databases to identify studies published from 1995 to 2009 on the epidemiology of HAI in African countries. No language restriction was applied. Available abstract books of leading international infection control conferences were also searched from 2004 to 2009.
Nineteen articles met the eligibility criteria for inclusion in the review; only two met high-quality criteria. Four relevant abstracts were retrieved from the international conference literature. Hospital-wide HAI prevalence varied between 2.5 and 14.8 per 100 patients; in surgical wards, the cumulative incidence ranged from 5.7 to 45.8 per 100 patients. Among specific types of infection, the largest number of studies focused on surgical site infection with a cumulative incidence ranging from 2.5 to 30.9 per 100 operated patients. Data on causative pathogens were available from a few studies only and highlighted the importance of Gram-negative rods, particularly in surgical site infection and ventilator-associated pneumonia.
Limited information is available on the endemic burden of HAI in Africa, but our review reveals that its frequency is several-fold higher than in developed countries. There is an urgent need to identify and implement feasible and sustainable approaches to strengthen HAI surveillance and control in Africa, including preventive strategies.
Disclosure of interest
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.