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  • Oral presentation
  • Open Access

Using innovative antimicrobial glove technology to reduce the risk of surgical wound contamination following glove perforation

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BMC Proceedings20115 (Suppl 6) :O33

  • Published:


  • Antimicrobial Activity
  • Risk Reduction
  • Clinical Efficacy
  • Whitney Test
  • Mann Whitney Test

Introduction / objectives

Surgical gloves create a protective barrier, however high perforation rates (6%>60%) are reported in the literature. A recent study has suggested linkage between glove perforation and increased risk of SSI. This investigation evaluated a model of microbial passage through conventional single (A), double-thickness (B) and a tri-layer innovative surgical glove (C) with antimicrobial activity.


Bacterial passage was assessed following multiple glove puncture using S. aureus and B. (Pseudomonas) diminuta (BD) in a model of gross wound contamination in volunteers in Groups A, B and C. Using microbiological methods bacterial passage was assessed at 5, 10, 30 and 45 minute exposure, expressed as cfu per unit time. A total of 6 repetitions were made for each glove/time interval. The Mann Whitney test was used to assess the differences in microbial passage between the three groups.


Microbial passage was evaluated separately (5, 10, 30 and 45 min) and combined (5/10 and 30/45). No significant differences were observed in microbial passage between Groups A and B at 10, 30, or 45 minutes, a significant difference was observed in Group C at 5, 30 and 45 minutes compared to A and B for SA and BD. When timed groups were combine a significant reduction in passage of SA and BD was observed compared to Groups A and B.


An antimicrobial surgical glove was effective at reducing microbial passage (p<0.05-p<0.005) following glove perforation compared to single or double-layer gloves. These findings suggest further studies are warranted to assess the clinical efficacy of an innovative antimicrobial glove technology as a SSI risk reduction strategy.

Disclosure of interest

None declared.

Authors’ Affiliations

Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
Ernst Moritz Amdt University, Greifswald, Germany


© Edmiston et al; licensee BioMed Central Ltd. 2011

This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.