Epidemiologic profile of Staphylococcus aureus-methicilin resistant (MRSA) bacterium in hospital-acquired-infection in neonatal-intensive-care-unit (ICU) from -2000 to 2010 analysis in general hospital
© Baqueiro-Freitas et al; licensee BioMed Central Ltd. 2011
Published: 29 June 2011
Introduction / objectives
Awareness of epidemiologic profile of MRSA-hospital-acquired infection in neonatal-ICU might improve an early recognition of this infection.
Evaluating the clinical epidemiologic profile of hospital-acquired Staphylococcus aureus-bacterium infection in neonatal-ICU patients according to its methicilin sensibility.
The infections cases were prospectively recorded for an eleven-year period from 2000 to 2010; the program used was EPI-INFO v 3.4.1.
31 strains of Staphylococcus sp were identified in some hospital-acquired-infections. 46.7% of Staphylococcus aureus were methicilin resistant. Bloodstream infection (BSI) was the most prevalent site of infection of MRSA (40%) as well as for methicilin-sensitive Staphylococcus aureus (MSSA) (62.5%). Symptoms of infection had began as early as 8.5 days and as late as 11 days (average time) from the admission date in methicilin-sensitive and methicilin-resistant Staphylococcus aureus cases respectively. The previous antibiotic therapy was more usual in MRSA cases (80%) than in MSSA (0%). The average weight of newborn infant was heavier in MSSA (2.222g) than MRSA (1626g). The frequency of death was higher in MRSA than MSSA (40% and 12,5% respectivelly). The average duration of stay was slightly longer in MRSA (24 days) than in MSSA (22.8 days).
From that analysis we have pointed out an epidemiologic profile of MRSA-hospital infections in neonatal-ICU concerning its prevalence and others epidemiologic issues in order to prevent its increase and diffusion in neonatal ICU.
Disclosure of interest
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