MRSA in pig farms: a prospective cohort study
© Cleef et al; licensee BioMed Central Ltd. 2011
Published: 29 June 2011
Introduction / objectives
The aims of this study were to determine the prevalence, determinants and dynamics of human carriage of livestock associated methicillin-resistant Staphylococcus aureus (MRSA) in pig farms.
In this prospective cohort study in 50 pig farms in The Netherlands, human nasal samples were collected on 5 time points in 8 months. At start of the study, throat samples and environmental samples were taken. Persistent carriers were defined as persons with 100% of nasal samples positive for MRSA, non-carriers had no MRSA and intermittent carriers had at least one positive sample. Data collection is still ongoing (total follow-up 1 year).
In total, 281 persons participated in the study. At start of the study, 21% of household members (31/147) and 68% of farmers/employees (90/132) were MRSA positive in nose or throat. Fifty-four persons were persistent MRSA carriers (54/281=19%): 5 household members (5/149=4%) and 49 farmers/employees (49/132=37%). Furthermore, 79 intermittent carriers and 148 non-carriers were found. Sixty-seven percent (33/49) of the residences and 80% (40/50) of the stables harboured MRSA. Working in the stables on a daily base and presence of MRSA in throat samples were significantly associated with persistent carriage (OR=12.7, 95%CI 4.1-39.3, and OR=5.0, 95%CI 2.3-10.9, respectively).
Persistent MRSA nasal carriage is common in persons working at pig farms. A possible explanation is the frequent exposure to high amounts of MRSA in the stables. Working in the stables still is an important factor in persistent carriage, as is throat carriage.
Disclosure of interest
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.