Acinetobacter Baumannii isolates: epidemiology, antibiogram and nosocomial status studied over a 25 month period in a tertiary care hospital in India
© Jaggi et al; licensee BioMed Central Ltd. 2011
Published: 29 June 2011
Introduction / objectives
The emergence of Acinetobacter baumannii as an epidemiologically significant nosocomial agent based on its epidemiology, antibiogram patterns and clinical correlation was explored in a 25 month study at a tertiary care hospital in India.
The Acinetobacter baumannii isolates over a twenty-five month period (Dec’08-Dec’10) were studied retrospectively for their antibiotic patterns, pathogenic stautus and epidemiology with special reference to nosocomial acquisition.
Superspeciality Tertiary care Indian hospital.
A. baumannii were isolated in 354 samples out of 3036 gram negative isolates (11.6% prevalence) from the entire hospital in the 25 month period. Maximum isolates were from respiratory secretions (59.8%) followed by blood (18.6%). Prevalence of A. baumannii rose to 29.5% (269 out of 909 gram negatives isolates) in ICU. The nosocomial status of A. baumannii was revealed in its contribution to 39.3% VAP, 38.7% CA-BSI, 12.6% SSI and 16.9% CA-UTI. Overall resistance of A. baumannii for carbapenems was 89% from all hospital isolates. ICU isolates showed higher resistance (92.9%) as compared to IPD (83.8%) and OPD (47.0%).
A. baumannii is mainly an ICU bug, showing 75.9% prevalence (269 isolates out of 354). Overuse of carbapenems in the ICU setting probably led to selection pressure and high level resistance of Acinetobacter to them. Hence implementation of antibiotic policy for judicious use of antibiotics should be stressed on. Also, one must prevent the nosocomial spread of Acinetobacter by appropriate infection control measures.
Disclosure of interest
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.