Table 1 Comparison of mAb production using ATF or TFF system at day 17 with cell densities maintained at 20-30 x 106 cells/mL.
ATF | TFF | |
|---|---|---|
Production in harvest (g) | 9 | 7 |
Yield (production in harvest/total production) (g/g in %) | 75 | 55 |
Total removal of mAb in cell bleeds/total production (g/g in %) | 19 | 30 |
Residual mAb mass in bioreactor/total production (g/g in %) | 6 | 15 |