Table 1 Linear dose-response relationships from reporter gene assays employing different human cell lines.
From: New reporter cell clones to determine the biological activity of human type I interferons
IFN | HEp L1D7 | HEp L1G5 | HeLa C5G6 | HeLa C6C3 | A549L2A6 | A549L2G9 |
|---|---|---|---|---|---|---|
IFN-α2a | 1.52 – 390 | 12.20 – 25,000 | 7.8 – 1,000 | 1.95 – 500 | 0.24 – 16 | 0.24 – 125 |
IFN-α2b | 0.76 – 390 | 12.20 – 50,000 | 7.8 – 1,000 | 1.95 – 500 | 0.24 – 4 | 0.24 – 8 |
IFN-β1a | 0.05 – 200 | 3.05 – 6,250 | 3.9 – 250 | 1.95 – 31.25 | 0.24 – 32 | 0.48 – 62 |
IFN-β1b | 3.05 – 200 | 12.20 – 50,000 | 3.9 – 1,000 | 3.90 – 500 | 0.24 – 32 | 0.48 – 62 |