Table 1 CD81 down-regulation in 293rVLP cells

5.8

20.4

88.4

92.8

10.0

31.0

98.5

CD81^- cells (%)

Specific cell growth (h^-1)

IC50 (µM tert-butyl hydroperoxide)

Specific RT productivity (10^-6 ng/cell.h)

2.1

0.0201 ± 0.0002

3.3 ± 1.1

1.7 ± 0.3

0.8

0.020 ± 0.002

9.2 ± 1.4

2.3 ± 0.4

86.4

0.0124 ± 0.0004

15.4 ± 1.0

0.9 ± 0.2

97.1

0.021 ± 0.002

4.5 ± 1.1

2.0 ± 0.4

92.9

0.015 ± 0.001

6.5 ± 1.1

1.2 ± 0.2

88.9

0.018 ± 0.001

6.0 ± 1.1

1.8 ± 0.4

82.3

0.017 ± 0.001

5.6 ±1.0

1.4 ± 0.2