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Table 1 Chemically defined feeds and hydrolysates tested

From: Medium and feed optimization for fed-batch production of a monoclonal antibody in CHO cells

Supplier

Commercial feed name

Feed name in the poster

ThermoFischer

Cell Boost 1

CD Feed 1

ThermoFisher

Cell Boost 2

CD Feed 2

ThermoFisher

Cell Boost 3

CD feed 3

ThermoFischer

Cell Boost 4

CD Feed 4

ThermoFischer

Cell Boost 5

CD Feed 5

ThermoFischer

Cell Boost 6

CD Feed 6

Life Tech

CHO Feed A

CD Feed 7

Life Tech

CHO Feed B

CD Feed 8

Life Tech

CHO Feed C

CD Feed 9

BD Biosciences

Yeast Extract

Hydrolysate 1

BD Biosciences

Yeastolate

Hydrolysate 2

BD Biosciences

Select Phytone

Hydrolysate 3

BD Biosciences

Ultrapep Soy

Hydrolysate 4

Sheffield

HyPep 1510

Hydrolysate 5

Sheffield

HyPep 4605

Hydrolysate 6

BD Biosciences

3 g/L Yeast Extract + 3.25 g/L Yeastolate

Hydrolysate combination 1

BD Biosciences

3.5 g/L Yeast Extract + 2.75 g/L Yeastolate

Hydrolysate combination 2

BD Biosciences

4 g/L Yeast Extract + 2.25 g/L Yeastolate

Hydrolysate combination 3

BD Biosciences

4.5 g/L Yeast Extract + 1.75 g/L Yeastolate

Hydrolysate combination 4

BD Biosciences

5 g/L Yeast Extract + 1.25 g/L Yeastolate

Hydrolysate combination 5

BD Biosciences

3 g/L Yeast Extract + 5.1 g/L Yeastolate

Hydrolysate combination 6

BD Biosciences

3.5 g/L Yeast Extract + 4.6 g/L Yeastolate

Hydrolysate combination 7

BD Biosciences

4 g/L Yeast Extract + 4.1 g/L Yeastolate

Hydrolysate combination 8

BD Biosciences

4.5 g/L Yeast Extract + 3.6 g/L Yeastolate

Hydrolysate combination 9

BD Biosciences

5 g/L Yeast Extract + 3.1 g/L Yeastolate

Hydrolysate combination 10