Figure 1
From: Stratify or adjust? Dealing with multiple populations when evaluating rare variants
Comparison of Q1 results from two gene-wise collapsing methods for rare variants. Each data point represents the results of meta-analysis of a single gene using the first 50 data replicates. The horizontal position is −log(p) from the analysis based on the Indicator variable; the vertical position is based on the Count variable. The correlation between the two values is 0.92. If we eliminate the top four values, the correlation is still 0.86.