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Table 1 Comparisons of penalized likelihood methods and group ISIS procedures 1 and 2 at three different noise levels

From: Detection of rare functional variants using group ISIS

Noise level

Penalized likelihood method

Group ISIS procedure 1

Group ISIS procedure 2

 

Group MCP

(with AIC)

Group MCP

(with BIC)

Group LASSO

(with AIC)

Group LASSO

(with BIC)

 

Group MCP

(with AIC)

Group MCP

(with BIC)

Group LASSO

(with AIC)

Group LASSO

(with BIC)

Q1

         

Low

45/4

8/4

168/1

168/1

12/5

8/5

5/4

4/4

4/4

Medium

89/5

10/4

216/1

147/1

12/5

9/5

7/5

5/5

3/3

High

233/3

121/3

233/1

177/1

12/2

24/2

22/2

13/2

13/2

Q2

         

Low

41/12

9/6

101/6

37/6

15/12

13/12

7/7

11/11

9/7

Medium

55/11

11/6

176/4

74/3

12/9

19/8

8/6

20/8

12/10

High

250/8

125/5

259/1

259/1

15/0

35/1

33/1

19/1

24/1

  1. In group ISIS procedure 2, penalized likelihood methods (group LASSO and group MCP) were used in the deletion step. The number of selected genes and the number of selected important genes (true positives) are reported.