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Table 2 Results of regression analysis of Q1 with the FLT1 gene in replicate 1

From: Are quantitative trait-dependent sampling designs cost-effective for analysis of rare and common variants?

Sampling design

Linear regression

Poisson regression

 

Coefficient

SE

Test statistic

p-value

Coefficient

SE

Test statistic

p-value

Rare variant score

1

0.44

0.08

5.18

4 × 10−7

0.60

0.11

5.59

2 × 10−8

2

0.43

0.11

3.81

2 × 10−4

0.55

0.13

4.14

3 × 10−5

3

0.71

0.14

4.94

2 × 10−6

0.68

0.13

5.26

1 × 10−7

4

0.80

0.14

5.59

1 × 10−7

0.79

0.14

5.81

6 × 10−9

5.1

0.30

0.11

2.82

5 × 10−3

0.61

0.11

5.37

8 × 10−8

5.2

0.15

0.10

1.48

0.14

0.63

0.11

5.58

2 × 10−8

Common variant C13S523

1

1.00

0.12

8.11

1 × 10−14

1.39

0.21

6.51

8 × 10−11

2

0.96

0.18

5.24

5 × 10−7

1.40

0.32

4.36

1 × 10−5

3

1.67

0.21

7.95

3 × 10−13

1.66

0.34

4.88

1 × 10−6

4

1.71

0.21

8.17

9 × 10−14

1.86

0.37

5.01

5 × 10−7

5.1

0.90

0.17

5.45

2 × 10−7

1.39

0.27

5.18

2 × 10−7

5.2

0.26

0.22

1.16

0.25

1.39

0.26

5.44

5 × 10−8

  1. P-values are based on the asymptotic distribution of the test statistic.