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Table 3 Simulation results for analysis of Q4 with the FLT1 rare variant score, replicates 1–200

From: Are quantitative trait-dependent sampling designs cost-effective for analysis of rare and common variants?

Sampling design

Linear regression

Poisson regression

 

Mean coefficient

Empirical SD

Mean SE

Type I error

Mean coefficient

Empirical SD

Mean SE

Type I error

1

−0.0014

0.042

0.044

0.040

−0.0089

0.254

0.233

0.075

2

−0.0044

0.060

0.062

0.040

−0.0280

0.364

0.333

0.065

3

−0.0025

0.083

0.086

0.040

−0.0076

0.270

0.246

0.060

4

−0.0031

0.079

0.083

0.030

−0.0127

0.274

0.252

0.050

5.1

−0.0007

0.045

0.046

0.045

−0.0025

0.304

0.281

0.070

5.2

−0.0004

0.051

0.046

0.105

−0.0142

0.274

0.251

0.070

  1. SD, standard deviation. SE, standard error.