Table 1 Type I error (5% significance level)
From: Comparison of statistical approaches to rare variant analysis for quantitative traits
MAF cutoff | Collapsing method (no common variants) | CMC method | LASSO method | ||||||
|---|---|---|---|---|---|---|---|---|---|
Indicator | Count | Data-adaptive | Indicator | Count | Data-adaptive | Indicator | Count | Data-adaptive | |
0.005 | 5.1 | 5.1 | 7.8 | 5.2 | 5.2 | 6.2 | 7.9 | 7.9 | 10.5 |
0.01 | 5.1 | 5.2 | 7.5 | 5.1 | 5.2 | 6.3 | 6.9 | 6.9 | 9.2 |
0.05 | 5.0 | 5.1 | 7.0 | 5.0 | 5.1 | 6.3 | 5.7 | 5.7 | 7.5 |