Table 2 Proportion of rare and common causal SNPs per risk gene
From: Comparison of statistical approaches to rare variant analysis for quantitative traits
Gene | MAF cutoff (number of causal SNPs/number of total SNPs) | |||||
|---|---|---|---|---|---|---|
0.005 | 0.01 | 0.05 | ||||
Rare | Common | Rare | Common | Rare | Common | |
ARNT | 4/14 | 1/4 | 4/15 | 1/3 | 5/17 | 0/1 |
ELAVL4 | 2/7 | 0/3 | 2/7 | 0/3 | 2/8 | 0/2 |
FLT1 | 8/24 | 3/11 | 8/25 | 3/10 | 10/32 | 1/3 |
FLT4 | 2/8 | 0/2 | 2/8 | 0/2 | 2/10 | 0/0 |
HIF1A | 3/6 | 1/2 | 3/7 | 1/1 | 4/8 | 0/0 |
HIF3A | 3/13 | 0/8 | 3/15 | 0/6 | 3/17 | 0/4 |
KDR | 8/14 | 2/2 | 8/14 | 2/2 | 9/15 | 1/1 |
VEGFA | 1/5 | 0/1 | 1/5 | 0/1 | 1/6 | 0/0 |
VEGFC | 1/1 | 0/0 | 1/1 | 0/0 | 1/1 | 0/0 |