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Table 2 p-value of the VEGF pathway for Affected Status and Q1 in the first simulation using different methods

From: Identifying rare disease variants in the Genetic Analysis Workshop 17 simulated data: a comparison of several statistical approaches

 

Affected Status

Q1, dichotomized

Q1 (Price et al. [9])

 

CMC

WS

RB

CMC

WS

RB

 

Rare NS

0.00287

<0.0001

<0.0001

2.938 × 10−6

<0.0001

<0.0001

<0.0001

Rare

0.06721

0.02

0.0003

0.02687

<0.0001

<0.0001

<0.0001

  1. Results from using only nonsynonymous rare variants (Rare NS) and all rare variants (Rare) are shown here. p-values for the WS and RB methods are computed based on 10,000 permutations.
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BMC Proceedings

ISSN: 1753-6561

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