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Table 2 Rank and nominal p-value from the association test between Q1 and the genes in the VEGF pathway included in the simulating model for Q1

From: Pathway analysis following association study

 

ARNT

ELAVL4

FLT1

FLT4

HIF1A

HIF3A

KDR

VEGFA

VEGFC

Rank

112

1,007

1

1,013

698

544

34

985

214

p-value

0.009

0.1359

2.4 × 10−13

0.1441

0.0885

0.0616

0.0017

0.1380

0.0186

  1. The smallest p-value from either single SNP association of common variants or aggregate of rare variants within a gene was chosen to represent the gene. All models were adjusted for age, sex, smoking, and principal components.
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BMC Proceedings

ISSN: 1753-6561

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